1-tert-butyl-3-(4-chloro-phenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine

A synthetic small molecule inhibitor primarily known as PP2. It is a potent and selective inhibitor of Src family tyrosine kinases (including Src, Lck, Fyn, and Yes), with additional activity against other kinases such as Abl and p38 MAP kinase. It is widely used in research to study signal transduction pathways involving these kinases but has not been approved for clinical use. The compound is considered experimental and has not advanced beyond preclinical or early-stage research phases. Its mechanism involves competitive inhibition at the ATP-binding site of target kinases.

Other names

1-Tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yamine1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amino4-amino-5-(4-chlorophenyl)-7-(tert-butyl)pyrazolo[3,4-d]pyrimidine